Desmopressin orally disintegrating tablet in Japanese patients with central diabetes insipidus: A retrospective study of switching from intranasal desmopressin
نویسندگان
چکیده
منابع مشابه
Comparison of Desmopressin (ddavp) Tablet and Intranasal Spray in the Treatment of Central Diabetes Insipidus
Desmoperssin is the drug of choice for treatment of central diabetes insipidus and most commonly it is used as intranasal spray. In this study, efficacy and side effects of oral desmopressin was compared with the intranasal spray. This study was before -after clinical trial on 14 outpatients (9 F, 5 M, age 14 -50 Y) with central diabetes insipidus who had been treated with intranasal spray of d...
متن کاملComparison of incidence of hyponatremia between intranasal and oral desmopressin in patients with central diabetes insipidus.
Central diabetes insipidus (CDI), which is characterized by polyuria and polydipsia, is caused by a deficiency of the antidiuretic hormone arginine vasopressin (AVP). While CDI is treated with desmopressin, an analogue of AVP, the intranasal formulation is inconvenient and CDI patients reportedly prefer the oral formulation to the intranasal one. In Japan, intranasal desmopressin had been the o...
متن کاملOral desmopressin in central diabetes insipidus.
Seven paediatric patients with central diabetes insipidus were studied in an open dose ranging study in hospital followed by a six month study on an outpatient basis to assess the efficacy and safety of peroral administration of DDAVP (desmopressin) tablets. In the dose ranging study a dose dependent antidiuretic response was observed. The response to 12.5-50 mcg was, however, less effective in...
متن کاملمقایسه اثربخشی دسموپرسین خوراکی با شکل اسپری آن در درمان دیابت بی‌مزه مرکزی
Desmopressin(intranasal spray or drop, IV injection or tablet) is a drug choice for the treatment of central diabetes insipidus and the intranasal spray is a more common treatment. In the present study, the efficacy and side effect of oral desmopressin was compared with the intranasal spray. This before-after clinical trial study was performed on 14 outpatients(9F, 5M, age 14-50Y) w...
متن کاملDiabetes insipidus and the use of desmopressin in hospitalised children.
There have been recent concerns raised about the hospital care of patients with diabetes insipidus and the morbidity and mortality associated with delay or omission of administration of desmopressin. This is a review of diabetes insipidus and desmopressin with a practical guide to management of these complex patients for the general paediatrician or intensive care physician caring for these chi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine Journal
سال: 2014
ISSN: 0918-8959,1348-4540
DOI: 10.1507/endocrj.ej14-0097